6. Drug-induced Leukoencephalopathy
نویسندگان
چکیده
منابع مشابه
Drug-Induced Progressive Multifocal Leukoencephalopathy: A Comprehensive Analysis of the WHO Adverse Drug Reaction Database.
OBJECTIVE To identify safety signals concerning the association between the use of various drug classes and the onset of progressive multifocal leukoencephalopathy (PML). METHODS All reports containing suspected or interacting PML-related or leukoencephalopathy-related drugs, held in the World Health Organization spontaneous individual case safety reports database as at 1 September 2014, were...
متن کاملTeaching NeuroImages: 5-FU-induced acute leukoencephalopathy.
A 55-year-old man with carcinoma sigmoid colon (fluorouracil [5-FU]: cumulative dose of 6,600 mg/m; and oxaliplatinum: 245 mg/m) presented with encephalopathy and pancerebellar involvement 2 weeks after receiving a third cycle of chemotherapy. Brain MRI showed diffusion restriction in bilateral deep white matter, cerebellar peduncles, and splenium of corpus callosum (figures 1 and 2) suggestive...
متن کاملLinezolid-induced posterior reversible leukoencephalopathy syndrome.
OBJECTIVE To describe a 71-year-old woman who developed clinical and neuroradiological features of posterior reversible leukoencephalopathy syndrome with a compromised blood-brain barrier after 5 days of intravenous linezolid therapy for an infected hip prosthesis. DESIGN Case report. SETTING Academic research. MAIN OUTCOME MEASURES Posterior reversible leukoencephalopathy syndrome was do...
متن کاملExecutive dysfunction in delayed radiation-induced leukoencephalopathy.
hospital for evaluation of a four-year history of progressive cognitive im pairment, irritable affect, gait impairment and incontinence. Thirty years earlier, she had undergone surgery and whole-brain radiotherapy (50 Gy in 25 fractions) for a right frontal oligodendroglioma. Her neurologic examination showed paratonia, primitive reflexes, hyperreflexia and difficulty initiating gait, despite p...
متن کاملMultifocal Demyelinating Leukoencephalopathy Induced by Levamisole Therapy
The neurotoxic effects of levamisole therapy have been rarely reported. In this article, we report two patients who developed multifocal demyelinating leukoencephalopathy (MDL) after levamisole treatment. Clinically, they had dizziness, nausea, vomiting, confusion, mental dullness, speechlessness, and memory impairment after the treatment. The total dosage of levamisole was 300 mg and 1800 mg, ...
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ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2007
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.96.1641